Modern Anesthetics

Von:Schwilden, Helmut; Schüttler, Jürgen; Schüttler, Jürgen; Schwilden, Helmut

ISBN: 9783540728139

ISBN-10: 3540728139

Artikelnummer: 135125

Lieferantenbestellnummer: 8598045

Springer-Verlag GmbH,Springer,Springer Berlin,

Ln ,2008 ,516 Seiten

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Part I: Molecular Mechanisms of Anesthetic Action.- The Site of Anesthetic Action. Inhibitory ligand-gated ion channels as substrates for general anesthetic actions. Actions of anesthetics on excitatory transmitter-gated channels. Voltage-Gated Ion Channels. G-Protein Coupled Receptors.- Part II: Modern Inhalation Anesthetics.- Inhalation anaesthesia: From diethyl ether to xenon. General Anesthetics and Long-term Neurotoxicity. Special Aspects of Pharmacokinetics of Inhalation Anesthesia. Inhalational Anaesthetics and Cardioprotection. Non-Immobilising Inhalational Anesthetic-Like Compounds.- Part III: Modern Intravenous Anesthetics.- Propofol. Pharmacokinetics and Pharmacodynamics of GPI 15715 or Fospropofol (Aquavan injection? ) - A Water-soluble Propofol Prodrug. Etomidate and Other Non-Barbiturates. Remifentanil and Other Opioids. Ketamine. Midazolam and Other Benzodiazepines.- Part IV: Pharmacokinetic: Dynamic Based Dosing Techniques of Anesthetics.- The Effect of Altered Physiological States on Intravenous Anesthetics. Anesthetics Drug Pharmacodynamics. Defining Depth of Anesthesia. Target controlled anaesthetic drug dosing. Advanced Technologies and Devices for Inhalational Anesthetic Drug Dosing. Hypnotic and Opioid Anesthetic Drug Interactions on the CNS, focus on response surface modeling.

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